Anti-IL-6/IL-6R antibodies and methods of use thereof

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S142100, C424S143100, C424S145100, C530S388100, C530S388150, C530S388220, C530S388230

Reexamination Certificate

active

08034344

ABSTRACT:
This invention provides fully human monoclonal antibodies that recognize the IL-6/IL-6R complex. The invention further provides methods of using such monoclonal antibodies as a therapeutic, diagnostic, and prophylactic.

REFERENCES:
patent: 5618700 (1997-04-01), Novick et al.
patent: 5670373 (1997-09-01), Kishimoto
patent: 5817790 (1998-10-01), Tsuchiya et al.
patent: 5888510 (1999-03-01), Kishimoto et al.
patent: 5990282 (1999-11-01), Kishimoto
patent: 6083501 (2000-07-01), Miyata et al.
patent: 6261250 (2001-07-01), Phillips
patent: 6410691 (2002-06-01), Kishimoto
patent: 6419944 (2002-07-01), Tobinick
patent: 6428979 (2002-08-01), Kishimoto
patent: 6723319 (2004-04-01), Ito et al.
patent: 2004/0028681 (2004-02-01), Ito et al.
patent: 2005/0074821 (2005-04-01), Wild et al.
patent: 2005/0100550 (2005-05-01), Trikha et al.
patent: 2005/0238644 (2005-10-01), Mihara et al.
patent: 2006/0134113 (2006-06-01), Mihara
patent: 2006/0165696 (2006-07-01), Hideuki
patent: 2006/0188502 (2006-08-01), Giles-Komar et al.
patent: 2006/0240012 (2006-10-01), Sugimura et al.
patent: 2006/0251653 (2006-11-01), Okuda et al.
patent: 2006/0257407 (2006-11-01), Chen et al.
patent: 2006/0292147 (2006-12-01), Yoshizaki et al.
patent: 2007/0036785 (2007-02-01), Kishomoto et al.
patent: 2007/0036788 (2007-02-01), Sheriff et al.
patent: 2007/0098714 (2007-05-01), Nishimoto et al.
patent: 2007/0148169 (2007-06-01), Yoshizaki et al.
patent: 2007/0207153 (2007-09-01), Fuijoka et al.
patent: 2007/0243189 (2007-10-01), Yoshizaki et al.
patent: 2007/0280945 (2007-12-01), Stevens et al.
patent: 2007/0292420 (2007-12-01), Giles-Komar et al.
patent: 2008/0124325 (2008-05-01), Hiroaki
patent: 2008/0145367 (2008-06-01), Bove et al.
patent: 0504307 (1994-01-01), None
patent: 0325474 (1995-05-01), None
patent: 0409607 (1996-10-01), None
patent: 0791359 (1997-08-01), None
patent: 1536012 (2005-06-01), None
patent: 4325095 (1992-11-01), None
patent: 10066582 (1998-03-01), None
patent: WO 95/09873 (1995-04-01), None
patent: WO 96/11020 (1996-04-01), None
patent: WO 96/12503 (1996-05-01), None
patent: WO 98/42377 (1998-10-01), None
patent: WO 99/47170 (1999-09-01), None
patent: WO 00/10607 (2000-03-01), None
patent: WO 2006/119115 (2006-11-01), None
patent: WO 2007/066082 (2007-06-01), None
patent: WO 2007/076927 (2007-07-01), None
patent: WO 2007/143168 (2007-12-01), None
patent: WO 2008/019061 (2008-02-01), None
patent: WO 2008/021237 (2008-02-01), None
patent: WO 2008/065378 (2008-06-01), None
patent: WO 2008/065384 (2008-06-01), None
patent: WO 2008/071685 (2008-06-01), None
Gaillard, et al., “Identification of a Novel Antigenic Structure of the Human Receptor for Interleukin-6 Involved in the Interaction with the Glycoprotein 130 Chain, ” Immunology, vol. 89(1): 135-141 (1996).
Grube, et al., “Identification of a Regulatory Domain of the Interleukin-6 Receptor,” J. Biological Chemistry, vol. 269(32): 20791-797 (1994).
Mizuguchi et al., “Enhanced signal transduction by a directly fused protein of interleukin-6 and its receptor,” J Biosci Bioeng., vol. 91(3):299-304 (2001).
Taga et al, “Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130,” Cell, vol. 58(3):573-81 (1989).
U.S. Appl. No. 09/762,550 as deposited on Feb. 9, 2001 with the U.S. Patent and Trademark Office.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Anti-IL-6/IL-6R antibodies and methods of use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Anti-IL-6/IL-6R antibodies and methods of use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-IL-6/IL-6R antibodies and methods of use thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4281254

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.