Anti-IL-12 antibodies and compositions thereof

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S130100, C424S139100, C530S387100, C530S387900, C530S388230, C530S389200

Reexamination Certificate

active

06902734

ABSTRACT:
The present invention relates to at least one anti-IL-12 antibody, including isolated nucleic acids that encode at least one anti-IL-12 antibody, IL-12, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.

REFERENCES:
patent: 5457038 (1995-10-01), Trinchieri et al.
patent: 5547852 (1996-08-01), Seller et al.
patent: 5648467 (1997-07-01), Trinchieri et al.
patent: 5780597 (1998-07-01), Gately et al.
patent: 5811523 (1998-09-01), Trinchieri et al.
patent: 5891680 (1999-04-01), Lieschke et al.
patent: 6086876 (2000-07-01), Karp et al.
patent: 6225117 (2001-05-01), Gately et al.
patent: 6300478 (2001-10-01), Trinchieri et al.
patent: 6338848 (2002-01-01), Leonard et al.
patent: 6495667 (2002-12-01), Bazan
patent: 790255 (1997-08-01), None
patent: 433827 (1998-03-01), None
patent: 804581 (2001-09-01), None
patent: WO 90/05147 (1990-05-01), None
patent: WO 92/05256 (1992-04-01), None
patent: WO 96 33735 (1996-10-01), None
patent: WO 97 15327 (1997-05-01), None
patent: WO 99/37682 (1999-04-01), None
patent: WO 99 37682 (1999-07-01), None
patent: WO 00 56772 (2000-09-01), None
patent: WO 00/56772 (2000-09-01), None
patent: WO 01/19373 (2001-03-01), None
A. U. Gubler et. al (Coexpression of Two Distinct Genes is Required to Generate Secreted Bioactive Cytotoxic Lymphocyte Maturation Factor) Proc. Natl. acad. Sci. USA. vol. 88. pp 4143-4147- (May 1991) Immunology.
A. U. Gubler et. al (Clonic and Expression of Cytotoxic Lymphocyte Maturation Factor (CLMF) a Heterodimeric Lymphokine That Potentiates NR. LAK NA D T-Cell Responses) Abstracts Journal of cellular Biochemistry Supplement 15 F: 70 (1991).
Alvin S. Stern et.al-(Purification to Homgeneity and Partial Characterization of Cytotoxic Lymphocyte Maturation Factor from Human B-Lymphoblastoid Cells) (Jun. 11, 1990) F. Hoffmann La Roche Inc. Nutley NJ USA. Proc. National Acad. Sci. USA (vol. 87,pp 6808-6812- Sep. 1990- Immunology).
M. Gately et. al. (Regulation of Human Lymphocyte Proliferation by a Heterodimeric Cytokine IL-12 (Cytotoxic Lymphocyte Maturation Factor) vol. 147- 874-882 No. 3. (Aug. 1, 1991).(The Journal of Immunology).
R. Chizzonite et. al. (IL-12 Monoclonal Antibodies Specific for the 40-KdA Subunit Block Receptor Binding and Biologic Activity on Activated Human Lymphoblasts.) vol. 147,1548-1556- No. 5 (Sep1, 1991) The Journal of Immunology.
Susan H. Chan et. al. (Introduction of Interferon Production by Natural Killer Cell Stimulatory Factor Characterization of the Responder Cells and Synergy with Other Inducers) (The Rockefeller University Press)- 0022-1007/91/04/0869/-vol. 173 Apr. 1991-pp869-879.
Annalisa D'Andrea et. al. (Production of Natural Killer Cell Stimulatory Factor (Interleukin 12) by Peripheral Blood Mononuclear Cell) J. Exp. Med. The Rockefeller university press- 0022-1007/92/11/1387 vol. 176 Nov. 1992. - pp: 1387-1398.
Markus F. Neurath et. al. (Antibodies to Interleukin 12 Abrogate Established Experimental Colitis in Mice) The Journal of Experimental Medicine-vol. 182- Nov. 1995- pp. 1281-1290.
R.W. Carter. et. al. (Production and Characterization of Monoclonal Antibodies to Human Interleukin-12) Hybriidona 16: 363-369 (1997).
Nicolas M. Valiante et. al. ( Role of the Production of Natural Killer Cell Stimulatory Factor (NKSF/IL-12) in the Ability of B Cell Lines to Stimulate T and NK Cell Proliferation). Cellunar Immunology 145, 187-198-(1992).
Rainer Duchmann et. al. ( Tolerance Towards Resident Intestinal Flora in Mice is Abrogated in Experimental Colitis and Restores by Treatment with Intelukin-1 or Antibodies to Interleukin-12) Eur. J. Immunol 196-26: 394-938.
Michiko Kobayashi et. al. I ( Identification and Purification of Natural Killer Cell Stimulatory Factor (NKSF) a Cytokine with Multiple Biologic Efects on Human Lymphocytes) J. Exp. Med. The Rockefeller university Press- vol. 170-(Sep. 1989) pp. 827-845.
Sylvie Trembleau et. al. (The Role of IL-12 in the Induction of Organ-Specific Autoimmune Diseases).
Nikhil, Ywalkar et al.; “Expression of interleukin-12 is increased in psoriatic skin”, Journal of Investigative Dermatology, Dec. 1998, pp. 1053-1057; vol. 111, No. 6; XP00800577; ISSN: 0022-202X, abstract.
PCT International Search Report PCT/US01/24720 dated Jul. 30, 2002.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Anti-IL-12 antibodies and compositions thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Anti-IL-12 antibodies and compositions thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-IL-12 antibodies and compositions thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3479336

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.