Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Anti-idiotypic
Patent
1994-07-21
2000-03-28
Schwadron, Ronald B.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Anti-idiotypic
4241331, 4241351, 4241841, 435327, 435328, 5303872, 5303873, 5303871, 530809, A61K 39395, C07K 1642, C12N 520
Patent
active
060428279
ABSTRACT:
Novel compositions and methods are described for stimulating a patient's immune system to tumor cells which bear a gp72 tumor-associated antigen and thereby eliciting a tumoricidal effect. Anti-idiotypic human monoclonal antibodies and idiotopic regions thereof to primary antibodies which bind selectively to an antigenic determinant of gp72 are provided to mediate the humoral and cellular components of the patient's immune system. The immunogenic agents find use both in vivo and in vitro.
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Austin Eric Bertram
Baldwin Robert William
Byers Vera S.
Durrant Linda Gillian
Cancer Research Campaign - Technology Limited
Schwadron Ronald B.
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