Anti-hypertensive piperidine compounds

Details Anti-hypertensive piperidine compounds Anti-hypertensive piperidine compounds

1986-06-24

1988-07-12

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514307, 514309, 514310, 514312, 514313, 514314, 514323, 544283, 546139, 546141, 546143, 546153, 546159, 546171, 546176, 546177, 546195, 546198, 546201, 546202, 546205, 546206, 546240, A61K 31445, C07D21110, C07D21112, C07D21114

Patent

active

047570792

ABSTRACT:
Novel compounds of the formula: ##STR1## are described wherein Z is a bicyclic aryl group containing between 9 and 10 ring atoms, up to two of which may be nitrogen and up to one of which may be oxygen or sulfur; A is an ethenyl group which may be lower-alkyl-substituted; and R and R' each represent H or an aliphatic group of 1-4 carbon atoms; or a pharmaceutically acceptable acid addition salt thereof.

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patent: 4478841 (1984-10-01), Audiau et al.
Sugiyama et al.; "Biolumin. Progr., Proc., Kanagawa-Ken, Jap. (1965), pp. 83-87.
C.A., 67:69165h, Sugiyama et al. (1967).

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