Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1989-09-15
1991-08-13
Robinson, Allen J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514149, 514558, 514563, 514564, 514579, 514610, 514645, A61K 3113, A61K 3120, A61K 31195, A61K 31655
Patent
active
050397052
ABSTRACT:
This invention concerns anti-hypertensive compositions and a method of lowering blood pressure in mammals. The active component of the compositions is a compound of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are independently chosen from straight chain and branched chain C.sub.1 -C.sub.12 alkyl groups and benzyl, with the proviso that no branch occur on the alpha carbon atom of the alkyl groups; or R.sub.1 and R.sub.2 together with the nitrogen atom they are bonded to form a pyrrolidino, piperidino, piperazino or morpholino group, M.sup.+ is a pharmaceutically acceptable cation, wherein X is the valence of the cation.
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Dunams Tambra M.
Hrabie Joseph A.
Keefer Larry K.
Wink David A.
Bailey John
Benson Robert
Robinson Allen J.
The United States of America as represented by the Department of
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