Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...
Reexamination Certificate
2006-03-21
2009-11-10
Stucker, Jeffrey (Department: 1649)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Structurally-modified antibody, immunoglobulin, or fragment...
C424S135100, C424S141100, C424S142100, C424S143100, C530S387300, C530S388100, C530S388150, C530S388220, C435S320100
Reexamination Certificate
active
07615215
ABSTRACT:
The present invention provides an antibody or peptide which immunologically reacts with human VEGF receptor Flt-1 and cells in which human VEGF receptor Flt-1 is expressed on the cell surface and an antibody or peptide which inhibits binding of human VEGF to human VEGF receptor Flt-1. It also provides a means for the diagnosis or treatment of diseases in which their morbid states progress by abnormal angiogenesis, such as proliferation or metastasis of solid tumors, arthritis in rheumatoid arthritis, diabetic retinopathy, retinopathy of prematurity, psoriasis, and the like.
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Hanai Nobuo
Ito Mikito
Kawada Yoko
Nakamura Kazuyasu
Shibuya Masabumi
Gucker Stephen
Kyowa Hakko Kirin Co., Ltd.
Nixon & Vanderhye P.C.
Stucker Jeffrey
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