Anti-human prohibitin antibodies

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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5303871, 5303877, 5303888, 435240, 435 27, 435 6, C07K 1600, C07K 1618, C07K 1630, C12Q 168

Patent

active

054630266

ABSTRACT:
An antibody which specifically binds with a human prohibitin or a partial structural fragment thereof can be used as a diagnostic agent in the detection of cancer. The human prohibitin has the structure illustrated in SEQ ID NO:1.

REFERENCES:
Nuell, et al., Prohibitn, an evolutionarily conserved intracellular protein the blocks DNA synthesis in normal fibroblasts and HeLa cells, Molec. Cell. Biol. vol. 11, pp. 1372-1381. 1991.

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