Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1996-04-05
1997-05-20
Eisenschenk, Frank C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303883, 5303891, 5303894, 5303879, C07K 1608, C07K 1600
Patent
active
056313500
ABSTRACT:
An anti-human influenza virus antibody is provided having the following characteristics: (a) specifically binds to the stem region of hemagglutinin of human influenza A virus subtype H3N2; (b) does not specifically bind to the stem region of hemagglutinin of human influenza A virus subtypes H1N1 and H2N2; and (c) does not specifically bind to the stem region of hemagglutinin of human influenza B virus. A composition comprising the antibody is also provided.
REFERENCES:
WPI Abstracts of Japanese Patent Publication No. 59-501714 dated Oct. 11, 1994.
Green et al., Cell, 28, 477-487 (1982) "Immunogenic Structure of the Influenza Virus Hemagglutinin".
Okuno et al., Report on 1st China-Japan International Congress of Virology, p. 47-48, (May 26-28, 1992), "Characterization of A Monoclonal Antibody Which Cross-Neutralized H1 and H2 Subtypes of Influenza A Virus".
Okuno et al., J. Virology, 67, No. 5, P.2552-2558, (May 1993) "A Common Neutralizing Epitope Conserved between the Hemagglutinins of Influenza A Virus H1 and H2 Strains".
Harns et al., Tibtech, 11:42, 1993.
Osband et al., Immunol. Today, 11:93, 1990.
Isegawa Yuji
Okuno Yoshinobu
Sasao Fuyoko
Ueda Shigeharu
Eisenschenk Frank C.
Takara Shuzo Co. Ltd.
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