Anti-human gastric cancer monoclonal antibody

Details Anti-human gastric cancer monoclonal antibody Anti-human gastric cancer monoclonal antibody

1989-12-06

1991-09-24

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 71, 435 79, 435 792, 435 794, 4351722, 43524027, 436501, 436503, 436536, 436548, 436540, 436 64, 436813, 530387, 530809, 935 95, 935103, 935106, 935110, G01N 3353, G01N 33567, C07K 1514, C12N 1500

Patent

active

050513559

ABSTRACT:
An anti-human gastric cancer monoclonal antibody, AMC-462, which belongs to the class IgG.sub.1, reacts with human digestive system cancer, and recognizes sialylated glycoproteins or glycolipids as the antigen is disclosed. It is effective for diagnosis of digestive system cancer, especially pancreatic cancer.

REFERENCES:
Del Villano et al., Clin. Chem., vol. 29, No. 3 (1983), 549:52.
Metzgar et al., P.N.A.S., vol. 81 (1984), 5242:46.
Imai et al., J. Immun., vol. 132, No. 6 (1984), 2992:97.

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