Anti-human adenocarcinoma antigen specific monoclonal antibody

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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530388, 530395, 530808, 530828, 435 7021, 43524027, 4351722, A61K 39395, C07K 1528, C12N 502

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050215531

ABSTRACT:
A monoclonal antibody against human cancer, characterized in that the monoclonal antibody is produced by a hybridoma cell line obtained from the fusion of B-lymphocyte immunized with cells of human cancer origin and tumor cells, and reactive with cancer cells from more than one organ but substantially not reactive with normal cells, and a process for production thereof; and a hybridoma cell line used to produce the above-mentioned monoclonal antibody, and a process for production thereof.

REFERENCES:
patent: 4569788 (1986-02-01), Mulshine et al.
patent: 4579827 (1986-04-01), Sakamoto et al.
patent: 4683200 (1987-07-01), Hirohashi et al.
Ochiai, A. et al., Jpn. J. Cancer Research, (GANN), 76(10): 915-918 (10-1985), cited in Medline Abstract No. 05784379 (1986).
Ochiai, A., et al., Gan Tokagaku Ryoho, 13 (4 PT2): 1416-1422, (4-1986), cited in Medline Abstract No. 05966838 (1986).
Biological Aspects, vol. 81, No. 44610, 1986.

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