Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Synthesis of peptides
Patent
1994-07-14
1996-07-02
Woodward, Michael P.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Synthesis of peptides
530370, A61K 3802
Patent
active
055322140
ABSTRACT:
A new protein, termed TAP 29, obtainable from the root tuber of the plant Trichosanthes kirilowii or produced by recombinant means is useful for treating HIV infections or tumors. In treating HIV infections, the protein is administered alone or in conjunction with conventional AIDS therapies. Also provided are processes for purifying the protein, DNA sequences encoding the protein, hosts expressing the protein, recombinant DNA methods for expressing the protein, and antibodies specific for the protein.
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Lee-Huang, S., et al, TAP 29: An Anti-human Immunodeficiency Virus Protein From Trichosanthes kirilowii that is Nontoxic to Intact Cells, Proc. Natl. Acad. Sci. USA, vol. 88, pp. 6570-6574, Aug. 1991.
Chen Hao-Chia
Huang Henry I.
Huang Paul L.
Huang Peter
Huang Philip L.
American Biosciences, Inc.
New York University
Stucker Jeffrey
The United States of America as represented by the Department of
Woodward Michael P.
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