Anti-HIV /Aids Chemo(C)-, immuno(I)-, or ci-therapy using tur (o

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514 21, 436512, 530827, 530868, 530350, 530413, 549 74, A61K 3138, A61K 3912

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active

057475261

ABSTRACT:
Herein described is an invention of the usage, design and effective procedures 1.) for selected combined methods for preparation and 2.) for coordination of sequence, dosage and administration in utilizing anti-HIV thiophenoyl urea TUR (or related drugs) chemotherapy as well as for utilizing HIV induced or augmented nonvirion antigen NVA (or early polypeptide vaccine EPV or related or derivative) immunotherapy in treatment of HIV+ and AIDS patients (and applicable to Karposi's sarcoma and to other retroviral diseases). Herein described is an invention of 3.) the usage, design and effective procedures for a combination of TUR and NVA (or similar elements) as specific active immunochemotherapy for the treatment of HIV positive and AIDS patients, which consists of a vaccine (NVA) composed of separated and concentrated early virus-induced or augmented nonvirion polypeptides which induce long-lasting cell-mediated immunity administered at the peak of effects by a synergistic antiviral drug, TUR, which causes minimal or no resistance.

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Cazzola et al. "In vivo modulating effect of a calf thymus acid lysate on human T lymphocite subsets and CD4/CD8 ration in the course of different diseases" Derwent 88-07429, 1987.
Eron et al. "Randomised tial of MNrgp120 HIV-1 vaccine in symptomless HIV-1 infection" Abst. Lancet v348, pp. 1547-1551, 1996.
Bolognesi "Prospects for prevention of and early intervention against HIV" JAMA v261, pp. 3007-3013, 1989.

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