Anti HIV-1 bacterial and baculovirus recombinant Epap-1

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S320100, C435S252300, C530S350000, C536S023100

Reexamination Certificate

active

07927831

ABSTRACT:
The invention relates to an anti HIV-1 active recombinant Epap-1 expressed in bacterial and baculovirus which significantly binds to gp120 of HIV-1 virus isolates.

REFERENCES:
patent: 191075 (2003-09-01), None
Kelvin Y. Kwan et al.; “Mice lacking DNA topoisomerase IIIB develop to maturity but show a reduced mean lifespan”; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA; PNAS, May 8, 2001, vol. 98, No. 10, pp. 5717-5721.
Secondo Sonza et al.; “Human Immunodeficiency Virus Type 1 Replication Is Blocked prior to Reverse Transcription and Integration in Freshly Isolated Peripheral Blood Monocytes”; Journal of Virology, Jun. 1996, vol. 70, No. 6, pp. 3863-3869.
Kondapi et al., “Anti-HIV activity of glycoprotein from first trimester placental tissue”, Antiviral Research, (2002), vol. 54, pp. 47-57.
Saiki et al., “Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase”, Science, (Jan. 29, 1988), vol. 239, No. 4839, pp. 487-491.

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