Anti-histaminic pyridyl compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514161, 514282, 546333, A61K 3144, C07D21355

Patent

active

046210946

ABSTRACT:
This disclosure describes compounds of formula I. ##STR1## wherein X is Cl or Br (including their pharmaceutically acceptable salts and esters) which have potent antihistamine activity and which are substantially free from sedative effects.

REFERENCES:
patent: 2567245 (1951-09-01), Sperber et al.
patent: 3862173 (1975-01-01), Carr et al.
patent: 4355036 (1982-10-01), Villani et al.
Burger, Medicinal Chem., J. Wiley, 3rd Edition, p. 76.
Kuntzman et al., Chem. Ab., vol. 71, Jul. 1969, 11415f.
Hucker et al., Drug Metabolism and Disposition, vol. 9 (5), pp. 428-433.
Buzas, J. Med. Chem., vol. 23, pp. 149-153 (1980).
Findlay et al., Aspet, May 16, 1980.
Physicians Desk Ref. (1978), pp. 707 and 708 Actidil and Actifed.
Kuntzman et al., Chem. Abstracts, vol. 71, 11415f (1969).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Anti-histaminic pyridyl compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Anti-histaminic pyridyl compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-histaminic pyridyl compounds will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-697394

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.