Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1996-04-18
1998-02-10
Hutzell, Paula K.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
435327, 435334, 53038885, 5303871, 4241411, 4241722, 4241522, 4241431, C12N 512, C07K 1600, A61K 39395
Patent
active
057170738
ABSTRACT:
The invention relates to anti-gp130 monoclonal antibodies, as well as to their uses for obtaining medicinal products, cell culture adjuvants and diagnostic reagents.
REFERENCES:
Wijdenes et al (Eur. J. Immunol., 1995, 25:3474-3481) Dec. 1995.
Johnston & Thorpe, Immunochemistry in Practice, Blackwell Scientific Pubs, Oxford, 1987, pp. 49-50.
The Journal of Biological Chemistry, vol. 267, No. 24, Aug. 25, 1992 Baltimore, MD pp. 16763-16766, J. Liu et al. "Interleukin-6 Signal Transducer GP130 Mediates Oncostatin M Signaling."
Journal of Immunological Methods, vol. 163, No. 2, Aug. 9, 1993 Amsterdam pp. 217-223, T. Saito et al. "Preparation Of Monoclonal antibodies against the IL-6 Signal Transducer, GP130, That Can Inhibit IL-6-Mediated Functions."
Biochemical and Biophysical Research Communications, vol. 185, No. 3, Jun. 30, 1992 Duluth, MN pp. 902-908, L. Snyers et al. "Enhancement Of IL-6 Receptor Beta Chain (GP130) Expression By IL-6, IL-1 And TNF In Human Epithelial Cells."
Proceedings of the National Academy of Sciences of the USA, vol. 89, No. 22, Nov. 15, 1992 Washington, DC pp. 10998-11001, T. Taga et al. "Functional Inhibition Of Hematopoietic and Neurotrophic Cytokines By Blocking The Interleukin 6 Signal Transducer GP130."
The 9th International Congress of Immunology; Meeting Sponsored By The American Association Of Immunologists And The International Union Of Immunological Societies, San Francisco, CA Jul. 23-29.
Annals of the New York Academy of Sciences, vol. 762, Jul. 21, 1995 New York, NY pp. 482-484, S. Chevalier et al. "Monoclonal Antibodies Define Different Functional Epitopes On GP130 Signal Transducer."
Clement Claude
Wijdenes John
Diaclone S.A. a Directoire et Conseil de Surveillance
Hutzell Paula K.
Ungar Susan
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