Anti-glaucoma compositions

Details Anti-glaucoma compositions Anti-glaucoma compositions

1991-07-12

1993-01-26

Michl, Paul R.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Aftertreated polymer

424427, 424428, 424486, 424487, 424501, 424 7818, 5147726, 514913, A61K 910, A61K 4732, A61K 31135, A61K 3114

Patent

active

051821028

ABSTRACT:
Ophthalmic pharmaceutical compositions useful in controlling elevated intraocular pressure associated with glaucoma and ocular hypertension are described. The compositions comprise a combination of a beta-blocker to reduce the production of aqueous humor and carbachol to enhance the outflow of aqueous humor. A method of controlling elevated intraocular pressure with those compositions is also described.

REFERENCES:
patent: 4256108 (1981-03-01), Theeuwes
patent: 4911920 (1990-03-01), Jani et al.
Remingtons Pharmaceutical Sciences, Mack Publishing Co., 1990.
Annual Reports in Medicinal Chemistry, 14:81-87 (1979).
J. Med. Chem., 26:1570-1576 (1983).
J. Med. Chem., 27:503-509 (1984).
J. Med. Chem., 26:7-11, 1561-1569, 1109-1112, 950-957, 649-657, 352-357 (1983).

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