Anti-glaucoma composition and method

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Lipid or oil

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A61K 3135

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active

041266951

ABSTRACT:
Tetrahydrodibenzopyrans having the structure ##STR1## in which R.sub.1 is hydrogen or acetyl and R.sub.2 is alkyl having from 1 to 4 carbon atoms are effective anti-glaucoma agents, free from all but a very small amount of CNS activity, when applied topically.

REFERENCES:
patent: 3668224 (1972-06-01), Petrzilka
patent: 3728360 (1974-04-01), Pars et al.
patent: 3734930 (1973-05-01), Razdan et al.
patent: 3799946 (1974-03-01), Loev
patent: 3920809 (1975-11-01), Thakkar
patent: 4025536 (1977-05-01), Korte et al.
Ophthalmologica 168:366-369 (1974)-D. Shapiro The Ocular Manifestations of the Cannabinols Newsweek, Nov. 8, 1976 -Pot and Glaucoma.
Chem. Abst. 83 158,044(r) (1975)-Purnell et al. ".DELTA..sup.9 -Tetrahydrocannabinol-in Man."
Chem. Abst. 84 130270(h) (1976) Green et al.-Interaction of--Tetrahydrocannabinol in the Eye."

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