Anti-fungal uracil compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514269, 544311, 544314, 544359, 544374, A61K 31495, A61K 31505, C07D23910, C07D40504

Patent

active

053468988

ABSTRACT:
Compounds of the formula ##STR1## wherein R.sub.3, R.sub.4, J, K, Z, and Het are as set forth herein are described.
The compounds of formula I are useful as agents in the treatment of fungal infections.

REFERENCES:
J. Org. Chem. 1986, 51, 2307-2314.
J. Med. Chem. 1986, 29, 802-809.
CA 106: 192579x and related computer printout, 1987.
New Synthetic Polyoxin Analogs for Chitin Synthesis Inhibition. Smith et al., Chitin Nat. Technol. 3rd, 1985 pp. 197-202.

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