Anti-fungal substance and preparing method thereof

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex

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A01N 908, A61K 3578

Patent

active

042006295

ABSTRACT:
Berberine type alkaloid is extracted from plant tissue containing the alkaloid with ethanol and contacted with phosphate. The obtained product has a high activity for inhibiting the growth of true fungi such as Blastomyces, Candida, Aspergillus and Trichophyton, and is used for curing human and animal diseases caused by the fungi.

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patent: 3541105 (1970-11-01), Melendez
patent: 3870727 (1975-03-01), Powell et al.
patent: 3879547 (1975-04-01), Thuillier
Henry, "The Plant Alkaloids", 4th Ed. (1949), published by The Blakiston Co., Phila. Pa., pp. 328-338, 344-345.
Tomita et al., Yakugaku Zasshi, vol. 78, pp. 1444-1447, (1958).
Chemical Abstracts, vol. 47:8175b.
Remington's Pharmaceutical Sciences, 13th Ed., (1965), Mack Publishing Co., pp. 820-823.
Dictionary of the Active Principles of Plants, (1894), Bailliere, Tendall & Cox, London, pp. 20 and 21.

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