Anti-fungal nail lacquer and method therefor

Compositions: coating or plastic – Coating or plastic compositions – Contains fireproofing or biocidal agent

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106 1505, 106 1832, 424 61, 514462, 523122, A61K 7043

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active

054877768

ABSTRACT:
An anti-fungal nail lacquer composition containing a film-forming agent, a solvent therefore, and an anti-fungal amount of griseofulvin which can be either in suspension or solution in the nail lacquer composition. A method of using the anti-fungal nail lacquer composition includes applying the composition to a finger or toenail and allowing the composition to remain in contact with the nail until the solvents evaporate and a thin film of griseofulvin remains on the nail.

REFERENCES:
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patent: 4557934 (1985-12-01), Cooper
patent: 4957730 (1990-09-01), Bohn et al.
Goldman et al, "Topical Griseofulvin Therapy Of That Which Is Called Tinea Pedis" Acts Dermato-Venereologica, vol. 39, pp. 454-460, 1959 [No Month].
Knight, "The Activity Of Various Topical Griseofulvin . . . In The Stratum Corneum", British Journal Of Dermatology, pp. 49-55, Nov. 1973.
Aal et al, "Topically Applied Griseofulvin In The Treatment Of Superficial Dermatomycoses In Egypt", Int Med Res 5, pp. 382-386, 1977 [No Month].
Epstein, "Topically Applied Griseofulvin In Prevention And Treatment Of Trichophyton Mentagrophytes", Arch Dermatol, vol. 111, pp. 1293-1297, Oct. 1975.
Zarowny et al, "Evaluatin Of The Effectiveness Of Griseofulvin . . . Dermatophytes", Journal Of Investigative Dermatology, 64: 268-272, 1975 [No Month].
Post et al, "Topical Treatment Of Experimental Ringworm In Guinea Pigs With Griseofulvin In Dimethylsulfoxide", Can Vet. J., 20:45-48, Feb. 1979.
Wallace et al, "Topically Applied Antifungal Agents", Archives Of Dermatology, vol. 113, pp. 1539-1542, Nov. 1977.

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