Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-01-13
1997-05-06
Tsang, Cecilia J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 21, 530324, 530350, 530380, A61K 3800, C07K 100
Patent
active
056271530
ABSTRACT:
The present invention relates to methods for treating fungal infection comprising administering to a subject suffering from a fungal infection a bactericidal/permeability-inducing (BPI) protein product.
REFERENCES:
patent: 5087569 (1992-02-01), Gabay et al.
patent: 5089274 (1992-02-01), Marra et al.
patent: 5126257 (1992-06-01), Gabay et al.
patent: 5171739 (1992-12-01), Scott
patent: 5198541 (1993-03-01), Elsbach et al.
patent: 5234912 (1993-08-01), Marra et al.
patent: 5308834 (1994-05-01), Scott et al.
patent: 5334584 (1994-08-01), Scott et al.
patent: 5348942 (1994-09-01), Little, II et al.
patent: 5420019 (1995-05-01), Theofan et al.
patent: 5447913 (1995-09-01), Ammons et al.
Davies, "Inactivation of Antibiotics and the Dissemination of Resistance Genes", Science, 264:375-381 (Apr. 15, 1994).
Eliopoulos and Moellering, "Antimicrobial Combinations", in Antibiotics in Laboratory Medicine, 3rd ed., pp. 432-492, (Lorian ed., Baltimore, MD) (1991).
Elsbach, "Antibiotics from within: Antibacterials from Human and Animal Sources", Trends. Biotech, 8(1):26-30 (Jan. 1990).
Elsbach et al., "Separation and Purification of a Potent Bactericidal/Permeability-Increasing Protein and a Closely Associated Phospholipase A.sub.2 from Rabbit Polymorphonuclear Leukocytes," J. Biol. Chem., 254:11000-11009 (1979).
Elsbach and Weiss, "Oxygen-Independent Antimicrobial Systems of Phagocytes," in Inflammation: Basic Principles and Clinical Correlates, pp. 603-636, (Gallin et al eds., Raven Press, Ltd.) (1992).
Elsbach and Weiss, "Oxygen-Independent Bactericidal Systems of Polymorphonuclear Leukocytes", in Advances in Inflammation Research, pp. 95-113, (Weissmann ed., Raven Press) (1981).
Gabay, "Ubiquitous Natural Antibiotics", Science, 264:373-374 (Apr. 15, 1994).
Gazzano-Santoro et al., "High-Affinity Binding of the Bactericidal/Permeability-Increasing Protein and a Recombinant Amino-Terminal Fragment to the Lipid A Region of Lipopolysaccharide", Infect. Immun., 60(11):4754-4761 (Nov. 1992).
Georgopapadakou and Walsh, "Human Mycoses: Drugs and Targets for Emerging Pathogens", Science, 264:371-373 (Apr. 15, 1994).
Gray et al., "Cloning of the cDNA of a Human Neutrophil Bactericidal Protein", J. Biol. Chem., 264(16):9505-9509 (Jun. 5, 1989).
Kanbe et al., "Evidence that Mannans of Candida albicans Are Responsible for Adherence of Yeast Forms to Spleen and Lymph Node Tissue", Infect. Immun., 61(6):2578-2584 (Jun. 1993).
Klotz and Smith, "Glycosaminoglycans Inhibit Candida albicans Adherence to Extracellular Matrix Proteins", FEMS Microbiology Letters, 99:205-208 (1992).
Levy et al., "Antibacterial 15-kDa Protein Isoforms (p15s) are Members of a Novel Family of Leukocyte Proteins", J. Biol. Chem., 268(8):6058-6068 (Mar. 16, 1993).
Mannion et al., "Preferential Binding of the Neutrophil Cytoplasmic Granule-Derived Bactericidal/Permeability Increasing Protein to Target Bacteria", J. Clin. Invest., 142(8):2807-2812 (Apr. 15, 1989).
Mannion et al., "Separation of Sublethal and Lethal Effects of Polymorphonuclear Leukocytes on Escherichia coli", J. Clin. Invest., 86:631-641 (Aug. 1990).
Mannion et al., "Separation of Sublethal and Lethal Effects of the Bactericidal/Permeability Increasing Protein on Escherichia coli", J. Clin. Invest., 85:853-860 (Mar. 1990).
Ooi et al., "A 25-kDa NH.sub.2 -terminal Fragment Carries All the Antibacterial Activities of the Human Neutrophil 60-kDa Bactericidal/Permeability-Increasing Protein", J. Biol. Chem., 262(31):14891-14894 (1987).
Ooi et al., "Endotoxin-neutralizing Properties of the 25 kD N-Terminal Fragment and a Newly Isolated 30 kD C-Terminal Fragment of the 55-60 kD Bactericidal/Permeability-Increasing Protein of Human Neutrophils", J. Exp. Med., 174:649-655 (Sep. 1991).
Ooi et al., "Isolation of Two Isoforms of a Novel 15-kDa Protein from Rabbit Polymorphonuclear Leukocytes that Modulate the Antibacterial Actions of Other Leukocyte Proteins," J. Biol. Chem., 265:15956-15962 (1990).
Sternberg, "The Emerging Fungal Threat", Science, 266(9):1632-1634 (Dec. 1994).
Stratton, "In Vitro Testing: Correlations Between Bacterial Susceptibility, Body Fluid Levels and Effectiveness of Antibacterial Therapy", in Antibiotics in Laboratory Medicine, pp. 849-879 (Lorian ed., Williams & Wilkins) (1991).
Veld et al., "Effects of the Bactericidal/Permeability-Increasing Protein of Polymorphonuclear Leukocytes on Isolated Bacterial Cytoplasmic Membrane Vesicles", Infect. Immun., 56(5):1203-1208 (May 1988).
Weiss and Olsson, " Cellular and Subcellular Localization of the Bactericidal/Permeability-Increasing Protein of Neutrophils", Blood, 69(2):652-659 (Feb. 1987).
Weiss et al., "Human Bactericidal/Permeability-Increasing Protein and a Recombinant NH.sub.2 -Terminal Fragment Cause Killing of Serum-resistant Gram-negative Bacteria in Whole Blood and Inhibit Tumor Necrosis Factor Release Induced by the Bacteria", J. Clin. Invest., 90:1122-1130 (Sep. 1992).
Weiss et al., "Resistance of Gram-negative Bacteria to Purified Bactericidal Leukocyte Proteins", J. Clin. Invest., 65:619-628 (Mar. 1980).
Weiss et al., "The Role of Lipopolysaccharides in the Action of the Bactericidal/Permeability-Increasing Neutrophil Protein on the Bacterial Envelope", J. Immunol., 132(6):3109-3115 (Jun. 1984).
Lambert, Jr. Lewis J.
Lim Edward
Little, II Roger G.
Scannon Patrick J.
Mohamed Abdel A.
Tsang Cecilia J.
Xoma Corporation
LandOfFree
Anti-fungal methods and materials does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Anti-fungal methods and materials, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-fungal methods and materials will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2132687