Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1989-08-25
1991-03-05
Friedman, Stanley D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
A61K 3113
Patent
active
049978543
ABSTRACT:
A class of anti-fibrotic agents and methods for their use as effective inhibitor substrate analogues of lysyl oxidase in-situ are provided. The inhibitory substrate analogues comprise adjacently positioned diamine compositions which may be employed in-vivo to therapeutically treat a wide variety of different pathological fibrotic diseases, disorders, and abnormalities.
REFERENCES:
The Journal of Biological Chemistry (vol. 254(16) pp. 7831-7836).
Chemical Abstracts (vol. 107): 35572t (1987).
Chemical Abstracts (vol. 105:221604p) (1986).
Gacheru Stephen N.
Kagan Herbert M.
Friedman Stanley D.
Prashker David
Trustees of Boston University
Weddington Kevin E.
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