Anti-FcRn antibodies for treatment of auto/allo immune...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C424S133100, C424S139100, C424S143100, C424S144100, C435S007100, C435S007210, C435S070210, C435S452000, C435S334000, C436S506000, C436S512000, C436S547000, C436S548000, C530S387300, C530S388700, C530S389300, C530S389600

Reexamination Certificate

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07662928

ABSTRACT:
Antibodies to heavy chain of human FcRn are provided which function as non-competitive inhibitors of IgG binding to FcRn. The antibodies may be polyclonal, monoclonal, chimeric or humanized, or antigen binding fragments thereof. These antibodies are useful for reducing the concentration of pathogenic IgGs in individuals and therefore used as a therapeutic tool in autoimmune and alloimmune conditions.

REFERENCES:
patent: 6992234 (2006-01-01), Roopenian
patent: 2002/0138863 (2002-09-01), Roopenian
patent: WO 2004035753 (2004-04-01), None
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