Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing
Patent
1993-09-01
1995-08-29
Reamer, James H.
Organic compounds -- part of the class 532-570 series
Organic compounds
Oxygen containing
C07C 4323
Patent
active
054462070
ABSTRACT:
Compounds of the formula: ##STR1## wherein a is a single bond and b is a double bond; or a is a double bond and b is a single bond; and enantiomers thereof; or a pharmaceutically acceptable salt thereof are described. These compounds can improve lipoprotein profile of dyslipidemic patients and generate an anti-atherogenic lipoprotein profile of normolipidemic individuals. In addition, inhibition of CETP activity may be useful as antifertility agents.
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JOC, vol. 51, No. 24, 28 Nov. 1986, pp. 45 68-4573 Sullivan, et al.
Studies on the Fauna of Curacao and Other Caribbean Islands, 62 (191): pp. 69-71 (1980).
Journal of Natural Products, vol. 54, No. 4, pp. 1108-1111, Jul.-Aug. (1991).
Tetrahedron, vol. 35, pp. 609-612 (1979).
Pure and Applied Chem., vol. 51, pp. 1893-1900 (1979).
Coval Stephen J.
Gullo Vincent P.
Horan Ann C.
Patel Mahesh G.
Pomponi Shirley A.
Boxer Matthew
Dicker Eric S.
Harbor Branch Oceanographic Institution Inc.
Nelson James R.
Reamer James H.
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