Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1984-05-31
1987-09-29
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Lymphokine
514255, 514309, 514378, 514866, A61K 3179, A61K 31495, A61K 3147, A61K 31415
Patent
active
046968156
ABSTRACT:
The invention is directed to novel galenic preparation forms for providing an oral anti-diabetic agent having an improved release of active substance and processes for producing these preparation forms. The novel pharmaceutical compositions are characterized in that the onset of the activity and the duration of activity are adapted to the particular needs of diabetics with regard to proper control of the metabolism and the associated proper release of insulin. A basic or acidic excipient in a solvent is added to the anti-diabetic active substance in a quantity such that the active substance is made soluble, and then a solubilizing agent is added. Polyvinyl pyrrolidone is dissolved as carrier in this solution, but the carrier may simultaneously serve as the solubilizing adjuvant. This solution is further processed with other excipients to form corresponding preparation forms.
REFERENCES:
patent: 3668215 (1972-06-01), Plumpe et al.
patent: 3669966 (1972-06-01), Amhrogi et al.
patent: 3708481 (1973-01-01), Kufter et al.
patent: 3883648 (1975-05-01), Ross et al.
patent: 4430399 (1984-02-01), Eistetter et al.
Brickl Rolf
Greischel Andreas
Rupprecht Eckhard
Schepky Gottfried
Brown Johnnie R.
Rollins John W.
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