Anti-diabetic peptides

Details Anti-diabetic peptides Anti-diabetic peptides

1998-08-21

2000-07-11

Davenport, Avis M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 530300, 530308, 530326, 4241841, 4241851, A61K 3800, A61K 3900, C07K 500, C07K 700

Patent

active

060873345

ABSTRACT:
Compounds of formula I which act as amylin agonists with respect to certain desired amylin activities and as calcitonin agonists with respect to certain desired calcitonin activities are provided. Such compounds are useful in treating disturbances in fuel metabolism in mammals, including, but not limited to diabetes mellitus, including Type I diabetes and Type II diabetes. The present invention also relates to methods of treating Type I diabetes, treating Type II diabetes and to methods of beneficially regulating gastrointestinal motility comprising administration of a therapeutically effective among of one of the compounds. Also provided are pharmaceutical composition comprising a compound of formula I and a pharmaceutically acceptable carrier.

REFERENCES:
patent: 5384250 (1995-01-01), Murgita
patent: 5814600 (1998-09-01), Rink et al.
patent: 5965528 (1999-10-01), Murgita

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