Anti-depressant spiro hexahydro arylquinolizine derivatives, com

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514210, 514219, 514234, 514248, 514250, 514257, 514278, 540203, 540353, 540492, 540493, 544 71, 544231, 546 18, A61K 31415, A61K 31305, C07D45500, C07D47120

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047105046

ABSTRACT:
Substituted hexahydro arylquinolizines and pharmaceutically acceptable salts thereof are selective .alpha..sub.2 -adrenergic receptor antagonists and thereby useful as antidepressants, antihypertensives, ocular antihypertensives, antidiabetics, platelet aggregation inhibitors, antiobesity agents, and modifiers of gastrointestinal motility.

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