Anti-depressant crystalline paroxetine hydrochloride hemihydrate

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

546197, A61K 31445, C07D40512

Patent

active

047217235

ABSTRACT:
The invention provides crystalline paroxetine hydrochloride hemihydrate, processes for its preparation, compositions containing the same and its therapeutic use as an anti-depressant.

REFERENCES:
patent: 4007196 (1977-02-01), Christensen
Chemical Abstracts, 95:54664z (1981) [Goethert, M., et al., Naunyn-Schmiedeberg's Arch. Pharmacol. 1980, 313(1), 21-6].
J. B. Lassen, Psychopharmacology, 57, pp. 151-153 (1978).
J. B. Lassen, European J. Pharmacol., 47, pp. 351-358 (1978).
J. Lund et al., Acta Pharmacol. et Toxicol., 44, pp. 289-295 (1979).
J. B. Lassen, et al., Psychopharmacology, 68, pp. 229-233 (1980).

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