Anti-D test and reagent

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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23230B, 252408, 2601125R, 424 12, G01N 3380

Patent

active

042960908

ABSTRACT:
Methods and reagents for determination of Rh (D) antigen in human blood. The reagent is a low-protein composition containing reduced and S-alkylated anti-D IgG maintained at pH of between about 7.5 and 8.3. This reagent meets or exceeds FDA standards for potency of anti-D for the slide test of rapid tube test.

REFERENCES:
patent: 2454752 (1948-11-01), Coca
patent: 2761810 (1956-09-01), Singher
patent: 2761811 (1956-09-01), Kupferberg
patent: 3579627 (1971-05-01), Hayakawa
patent: 3880988 (1975-04-01), Fly
"A Seminar on Performance Evaluation", Byron A. Myhre, ed., presented at the 29th Annual Meeting of the American Association of Blood Banks in San Francisco, Calif. on Nov. 2, 1976, American Association of Blood Banks, Central Office, Suite 608, 1828 L Street, N.W., Washington, D.C. 20036.
Romans, et al. Proc. Natl. Acad. Sci., U.S.A., 74(6), 2531-2535 (1977).
Laschinger, et al., Abstract (report of the Combined Meeting of the XVII Congress of The International Society of Hematology and The XV Congress of the International Society of Blood Transfusion, Jul. 24-28, 1978).

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