Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using tissue cell culture to make a protein or polypeptide
Patent
1996-07-18
1999-12-07
Teng, Sally
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Using tissue cell culture to make a protein or polypeptide
5303881, 53038815, 53038822, C12N 512, C07K 1628
Patent
active
059981725
ABSTRACT:
The present invention relates, in general, to CD6 and, in particular, to a CD6 ligand present on the surface of thymic epithelial cells, monocytes, activated T cells and a variety of other cell types. The invention further relates to methods of inhibiting the interaction of CD6 and the CD6 ligand, and to methods of screening compounds for their ability to inhibit that interaction. The invention also relates to antibodies, and binding fragments thereof, specific for CD6 ligand.
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Aruffo Alejandro
Bowen Michael A.
Haynes Barton F.
Marquardt Hans
Patel Dhavalkumar D.
Bristol--Myers Squibb Company
Duke University
Teng Sally
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