Anti-cancer drugs for the treatment of melanomas and method for

Details Anti-cancer drugs for the treatment of melanomas and method for Anti-cancer drugs for the treatment of melanomas and method for

1982-04-14

1983-11-08

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424 85, A61K 3944, C07G 700

Patent

active

044141483

ABSTRACT:
The present invention relates to drugs useful in particular for the treatment of melanomas, characterized in that they contain an active substance which is a molecule in which the chain A of ricin is associated, by a covalent bond of disulfide type, with a human antimelanoma antibody.

REFERENCES:
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Proc. Nat. Acad. Sci. USA, 77(4), 2183-2187, (1980), Woodbury et al.
Chem. Abstracts, vol. 95, 1981, 35295p, Blythman et al.
Chem. Abstracts, vol. 94, 1981, 132084f, Pau et al.
Biol. Abstracts, vol. 71, 1981, 68145, Youle et al.
Biol. Abstracts, vol. 71, 1981, 68063, Yasuhiko et al.
Biol. Abstracts, vol. 71, 1981, 32655, Krolick et al.
Biol. Abstracts, vol. 71, 1981, 46810, Gilliland et al.
Biol. Abstracts, vol. 71, 1981, 46871, Jansen et al.
Biol. Abstracts, vol. 71, 1981, 68064, Miyazaki et al.

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