Anti-cancer compounds

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

Reexamination Certificate

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Details

C435S117000, C435S007100, C424S009100, C562S433000, C530S300000, C530S314000, C530S333000, C530S402000

Reexamination Certificate

active

07427496

ABSTRACT:
The invention provides bradykinin antagonists and pharmaceutically acceptable salts thereof having anti-cancer activity. These anti-cancer compounds are particularly useful for inhibiting the growth of lung and prostate cancers.

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patent: 5635593 (1997-06-01), Cheronis et al.
patent: 5849863 (1998-12-01), Stewart
patent: 6388054 (2002-05-01), Stewart et al.
patent: 7071168 (2006-07-01), Stewart et al.
patent: WO 97/09347 (1997-03-01), None
L. Gera et al.; “New Bradykinin Antagonists Having High Potency at Both B1 and B2 Receptors”; Chemistry, Structure and Biology, Mayflower Scientific Ltd., 1996, pp. 348-349.
D. Chan et al.; “Novel Bradykinin Antagonist Dimers for the Treatment of Human Lung Cancers”; Immunopharmacology, vol. 33, 1996, pp. 201-204.
Stewart et al.; Can. J. Physical. Pharmacol. 75:719-724, 1997.

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