Anti-bile acid antibodies and method for assaying bile acids in

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 795, 5303892, G01N 33543, C07K 1618

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active

056019939

ABSTRACT:
Bile acids in the feces can be easily examined on a mass scale. Further, colon cancer at an early stage can be detected and the latent colon cancer can be diagnosed. The concentration of primary bile acid (CA) in the feces is measured by an ELISA method with the use of an anti-bile acid antibody for primary bile acid which comprises anti-cholic acid-24-bovine serum-rabbit serum, the concentration of secondary bile acid (DCA) in the feces is measured by an ELISA method with the use of an anti-bile acid antibody for secondary bile acid which comprises anti-deoxycholic acid-24-bovine serum-rabbit serum, and the concentration ratio (DCA/CA) of the secondary bile acid to the primary bile acid is calculated from the measured values.

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