Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1994-06-10
1997-02-11
Ceperley, Mary E.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 795, 5303892, G01N 33543, C07K 1618
Patent
active
056019939
ABSTRACT:
Bile acids in the feces can be easily examined on a mass scale. Further, colon cancer at an early stage can be detected and the latent colon cancer can be diagnosed. The concentration of primary bile acid (CA) in the feces is measured by an ELISA method with the use of an anti-bile acid antibody for primary bile acid which comprises anti-cholic acid-24-bovine serum-rabbit serum, the concentration of secondary bile acid (DCA) in the feces is measured by an ELISA method with the use of an anti-bile acid antibody for secondary bile acid which comprises anti-deoxycholic acid-24-bovine serum-rabbit serum, and the concentration ratio (DCA/CA) of the secondary bile acid to the primary bile acid is calculated from the measured values.
REFERENCES:
patent: 4207308 (1980-06-01), Spenney
patent: 4256724 (1981-03-01), Rutner et al.
patent: 4264514 (1981-04-01), Hixson, Jr. et al.
patent: 4273866 (1981-06-01), Voss et al.
Kouda et al., Evaluation of Immunological Test Kit (OC-HEMODIA) for Routine Clinical Examinal of Fecal Occult Blood, Yakuri to Chiryo vol. 16, No. 3, Mar. 1988, pp. 173-181.
Gan no Rinsho, vol. 33, No. 9, Aug. (1987) pp. 48-61 with Japanese Abstract.
Igaku no Ayumi, vol. 147, No. 5 (1988) pp. 395-398 with English Abstract.
Hill, Bile Flow and Colon Cancer, Mutation Research, 238 (1990) pp. 313-320.
Medical Practice, vol. 8, No. 6 (1991) pp. 879-881, English Abstract.
Hill, The Role of Unsaturated Bile Acids in the Etiology of Large Bowel Cancer, (1977) pp. 1627-1640.
Kaibara et al., Fecal Bile Acids and Neutral Sterols . . . , Oncology, vol. 40, pp. 255-258 (1983) pp. 953-954.
Tanida et al., Fecal Bile and Analysis in Healthy Japanese . . . , Gastroenterologia Japonica, vol. 16, No. 4, (1981), pp. 363-202.
Wakayama Igaku, (1986), 37 (3) pp. 195-202, English abstract.
Igaku no Ayumi, vol. 149, No. 13, (1989), pp. 953-954, English abstract.
B. Erlanger, Methods in Enzymology, vol. 70, pp. 85-105 (1980).
R. Moorehead et al., Gut, vol. 28, pp. 1454-1459 (1987).
R. Owen et al., Nutrition and Cancer, vol. 9, pp. 67-71 (1987).
N. Rose et al., Manual of Clinical Laboratory Immunology, Third Edition, pp. 99-109, American Society for Microbiology, Washington, D.C. (1986).
Takashima et al., "Carcinogenesis in the Residual Large Bowel and Change in Metabolism of Bile Acid After Right Colectomy in Rats", Igaku no Ayumi, vol. 147, No. 5 (1988) pp. 395-398 (Full English translation).
Kano Motonari
Matsumoto Masaru
Motegi Koki
Wada Hiroshi
Ceperley Mary E.
Yamato Jihan Kabushikigaisha
Yuugengaisha B.S.R.
LandOfFree
Anti-bile acid antibodies and method for assaying bile acids in does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Anti-bile acid antibodies and method for assaying bile acids in , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-bile acid antibodies and method for assaying bile acids in will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-341110