Anti-bacterial substances and microorganisms which produce them

Details Anti-bacterial substances and microorganisms which produce them Anti-bacterial substances and microorganisms which produce them

1993-08-02

1994-09-13

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

424122, 435119, 549239, 549245, 560126, 562508, A61K 3134, C07D30793, C12P 740

Patent

active

053469194

ABSTRACT:
The present invention relates to the compound A of the formula (A), the related compound B, carboxylic acid derived from acid anhydride group of these compounds and esters and salts thereof, microorganisms for producing the compounds, methods for producing the compounds A and/or B by using the microorganisms, and a treated or untreated fermentation broth obtained by culturing strains belonging to genus Zopfiella or Zopfiella curvata No. 37-3 strain. ##STR1## The present invention provides the compounds A and B, derivatives thereof, and treated or untreated fermentation broth obtained by culturing the strains belonging to genus Zopfiella or Zopfiella curvata No. 37-3 strain, which show an excellent activities as antifungal agent and anti-thrombotic agent.

REFERENCES:
Abstract No. 140553a, Chemical Abstracts, vol. 82, No. 22, Jun. 2, 1975, Columbus, Ohio, U.S. and Dror, M. et al., J. Polym. Sci., Polym. Chem. Ed., vol. 13, No. 1, 1975, pp. 171-187.

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