Anti-bacterial compound and pharmaceutical compositions thereof

Details Anti-bacterial compound and pharmaceutical compositions thereof Anti-bacterial compound and pharmaceutical compositions thereof

1993-01-08

1994-03-08

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D49504, A61K 3140

Patent

active

052928926

ABSTRACT:
The present invention relates to a novel antibacterial compound obtainable from the genus Alteromonas and which shares structural similarity with the pseudomonic acids.

REFERENCES:
Ernst B. Chain et al, "Pseudomonic Acid. Part 1. The Structure of Pseudomonic Acid A, a Novel Antibiotic produced by Pseudomonas fluorescens", (1977), pp. 294-322, J. Chem. Soc. Perkin Trans. I.
J. Peter Clayton et al, "The Chemistry of Pseudomonic Acid. Part 5., Structure and Chemistry of Pseudomonic Acid C. X-Ray Crystal Structure of Ethyl Monate C", (1982), pp. 2827-2833, J. Chem. Soc., Perkin Trans. I.
Peter J. O'Hanlon et al, "The Chemistry of Pseudomonic Acid. Part 6. Structure and Preparation of Pseudomonic Acid D", (1983) pp. 2655-2657, J. Chem. Soc. Perkin Trans. I.
D. B. Stierle et al, "Pseudomonic Acid Derivatives from a Maine Bacterium", Abstracts of Papers, 200(2), Part 2, 20th ACS National Meeting, American Chemical Society (1990).
Liettlinger et al, "Stoffwechselprodukte von Actinomyceten" (1959), pp. 563-568, No. 61, Helvetica Chimica Acta, 42.
Walter D. Celmer et al, "The Structures of Thiolutin and Aureothricin, Antibiotics Containing a Unique Pyrrolinonodithiole Nucleus", (1955), pp. 2861-2865, Structure of Thiolutin and Aureothricin.
Angew. Chem., vol. 66, (1954), 745.
Walter D. Celman et al, "Characterization of the Antibiotic Thiolutin and its Relationship with Aureothricin", (1952), pp. 6304-6305, JACS, 74.

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