Anti-bacterial and anti-cancer spiro beta-lactone/gamma-lactams

Details Anti-bacterial and anti-cancer spiro beta-lactone/gamma-lactams Anti-bacterial and anti-cancer spiro beta-lactone/gamma-lactams

2007-07-31

2007-07-31

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S410000

Reexamination Certificate

active

11146613

ABSTRACT:
Disclosed herein are novel spiro beta-lactone/gamma lactams for use in treating bacterial infections and cancer. The compounds are characterized by a terminal electron-withdrawing group such as a nitro group. Screening data shows antimicrobial activity against various bacterial cell lines, particularly gram-positive bacteria, and anti-cancer activity.

REFERENCES:
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