Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-09-17
1988-10-18
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514826, 548253, A61K 3141
Patent
active
047788160
ABSTRACT:
5-(3-n-Butyloxalylaminophenyl) tetrazole having an excellent SRS-A release-inhibiting effect is used as an effective component for an anti-asthmatic agent, and a pharmaceutical preparation obtained by mixing the tetrazole with a specific dispersant such as polysorbate-80 in coexistence with a non-aqueous solvent shows high dissolubility and bioavailability.
REFERENCES:
patent: 4400381 (1983-08-01), Favier et al.
patent: 4432986 (1984-02-01), Frickson et al.
patent: 4442115 (1984-04-01), Ramspen et al.
patent: 4443460 (1984-04-01), Rodriquez et al.
Chemical Abstracts 96: 217856 a (1982).
Agata et al., Japan. J. Pharmacol. 32:689-697 (1982).
May et al., J. Allerg., vol. 46, No. 1, pp. 12-20 (1970).
Abe Tooru
Hashimoto Terumasa
Kageyama Shinji
Kohno Shigekatsu
Kuroda Toshio
Schenkman Leonard
Wakamoto Pharmaceutical Co., Ltd.
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