Anti-arthritic herbal composition and method thereof

Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from zingiberaceae

Reexamination Certificate

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C424S725000

Reexamination Certificate

active

07338674

ABSTRACT:
The invention provides a novel herbal composition for treatment of arthritis and inflammation. The herbal composition comprises a therapeutically effective combination of extracts obtained from the plantsTerminalia chebula, Pluchea lanceolata, Desmodium gangeticum, Vitex neguntoandZingiber officinale, optionally along with pharmaceutically acceptable additives. The invention further comprises methods of making the herbal composition and methods of use for the treatment of arthritis and inflammation.

REFERENCES:
patent: 2001/0046523 (2001-11-01), Newmark et al.
Rege et al. “Adaptogenic Properties of Six Rasayana Herbs Used in Ayurvedic Medicine,” Phytotherapy Research, 13, 275-291 (1999) (17 pages total).
Srivastava et al. (“Anti-inflammatory Activity ofPluchea lanceolata: Isolation of an Active Principle,” Int. J. Crude Drug Res., 28: 135-137; 1990) (3 pages total).
Internet website “Herbal Monograph-Vitex negundo” (2002) (1 page total).
Ghosh et al. “Anti-inflammatory and Analgesic activities of Gangelin- A Pterocarpenoid form Desmodium Gangeticum,” Ind. J. Pharmac, 1981, 15 (4) 391-402. (12 pages total).
Atal, C., et al., “Screening of Indian Plants for Biological Activity: Part VIII,”Indian Journal of Experimental Biology, 1978, pp. 330-349, vol. 16.
Chaturvedi, G.N. and R.H. Singh, “Experimental Studies on the Antiarthritic Effect of Certain Indigenous Drugs,”Ind. Jour. Med. Res., 1965, pp. 71-80, vol. 53(1).
Dasgupta, B., “Chemical Investigation ofPluchea lanceolataI. Isolation of a New Quarternary Base, Pluchine,”Experientia, 1967, pp. 989-991, vol. 23.
Dasgupta, B., et al., “Chemical Investigation ofPluchea lanceolata, II. Identity of Pluchine with Betaine Hydrochloride,”Experientia, 1968, pp. 862, vol. 24.
Karandikar, G., et al., “Anti-Inflammatory Activity of Some Ayurvedic Remedies and their Influence on the Hypophyseo-Adrenocortical Axis in White Rats,”Ind. Jour. Med. Res., 1990, pp. 482-487, vol. 48(4).
Prasad, D.N., “Preliminary Photochemical and Pharamacological Studies onPlutchea lanceolata, Linn,”Ind. Jour. Med. Res.,1965, pp. 1062-1068, vol. 53(11).
Prasad, D.N., “A Study of Anti-Inflammatory Activity of Some Indigenous Drugs in Albino Rats,”Ind. Jour. Med. Res., 1966, pp. 582-590, vol. 54(6).
Prasad, S. and R. Mitra, “Pharmacognostical Studies on Rasna (Pluchea lanceolata. C.B. Clarke & Olive,”Jour. Res. Ind. Med., 1970, pp. 59-76, vol. 5(1).
Prasad, S., et al., “Pharmacognostic Study of Leaves ofPluchea lanceolataC.B. Clarke & Olive (Rasna),”Jour. Res. Ind. Med., 1970, pp. 203-207, vol. 4(2).
Singh, R.H. and G.N. Chaturvedi, “Inhibition of Formaldehyde Induced Arthiritis by Certain Indigenous Drugs,”Ind. Jour. Med. Res., 1966, pp. 188-195, vol. 54(2).

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