Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1997-06-04
2000-07-04
Jones, Dwayne C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514648, A01N 3302, A61K 31135
Patent
active
060839910
ABSTRACT:
Pharmaceutical compositions for the treatment of cardiac arrhythmia comprising an effective anti-arrhythmic amount of at least one compound in association with a pharmaceutically acceptable, substantially non-toxic carrier or excipient, the compound having one of the formulae (I) or (II) or a salt thereof with a pharmaceutically acceptable acid, and methods for the treatment of cardiac arrhythmia or effecting anti-arrhythmic action which comprise administering to a patient requiring anti-arrhythmic therapy or effect at least one of the above-described compounds.
REFERENCES:
patent: 5091576 (1992-02-01), Bergeron
Marmo et al., "Cardiovascular and respiratory effects of spermidine and spermine", Biomed. Biochim. Acta 43(4), pp. 509-515, 1984.
Kecskemeti et al., "Modification of the cardiac transmembrane potentials and currents by polyamines", Eur. J. Pharmacol. 142(2), pp. 297-303, 1987.
Clarke Dennis P.
Jones Dwayne C.
University of Florida Research Foundation Inc.
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