Anti-arrhythmic agents

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260268TR, 26029361, 260326C, 260326R, 2603433R, 42424854, 424250, 424267, 424274, C07D41306, C07D20994, C07D40106, C07D40306

Patent

active

040187675

ABSTRACT:
A series of 5-endo-(1-naphthoyloxy)-N-[amino-(lower)alkyl]bicyclo[2.2.1]heptane-2,3-di -endo-carboxylic acid imides have been found to possess unique prophylactic and therapeutic activity as anti-arrhythmia agents. An example of such a compound possessing excellent activity is 5-endo-(1-naphthoyloxy)-N-(3-dimethylaminopropyl)bicyclo[2.2.1]heptane-2,3 -di-endo-carboxylic acid imide hydrochloride.

REFERENCES:
patent: 3850921 (1974-11-01), Matuo et al.
patent: 3850922 (1974-11-01), Matuo et al.
patent: 3936449 (1976-02-01), Matuo et al.
Morrison et al., Organic Chemistry, pp. 1040-1043, (1969).

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