Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-08-06
1981-07-21
Raymond, Richard
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544335, 544357, 26032625, 544374, 546187, 26032636, 546207, 546214, 260330, 548200, 548214, 2603406, 548215, 548240, 2603409R, 548300, 548356, 2603457R, 2603458R, 2603459R, 2603473, 2603474, 42424854, 424250, 424251, 424267, 424270, 424273R, 424274, 424275, 424278, 424283, 424285, 544 3, 544 54, 544 584, 544 63, 544 87, 544 96, 544148, 544149, 544152, 544238, 544296, A61K 3134, A61K 3135, A61K 31335, C07D30724
Patent
active
042799023
ABSTRACT:
Acetamide derivatives are provided having the structure ##STR1## wherein X is a single bond, --CH.sub.2 -- or --O--, R.sup.1 and R.sup.2 may be the same or different and are lower alkyl, phenyl-lower alkoxy-lower alkyl, lower alkenyl, phenyl-lower alkyl or lower alkoxy, or ##STR2## may be taken together to form a 5- to 7-membered heterocyclic ring optionally containing one other hetero atom, such as nitrogen, sulfur or oxygen; Y is hydroxyl, OR wherein R is lower alkyl, lower alkenyl or lower alkanoyl, or ##STR3## wherein R.sup.1 and R.sup.2, and R.sup.1 and R.sup.2 taken together with the nitrogen to which they are attached are as defined above, and n is 1 to 6.
These compounds are useful as anti-arrhythmia agents and have been found to be effective in the treatment of acute myocardial infarction.
REFERENCES:
Mukai et al., Chemical Abstracts, vol. 80 (1974) 97,333y.
Hauck Frederic P.
Jacobs Glenn A.
E. R. Squibb & Sons Inc.
Levinson Lawrence S.
Raymond Richard
Rodney Burton
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