Anti-apoptosis genes and methods of use thereof

Chemistry: molecular biology and microbiology – Plant cell or cell line – per se ; composition thereof;... – Plant cell or cell line – per se – contains exogenous or...

Reexamination Certificate

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C536S023600, C435S320100

Reexamination Certificate

active

10167015

ABSTRACT:
The invention provides isolated nucleic acids and their encoded proteins that act as cell death inhibitors and methods of use thereof. The invention further provides expression cassettes, transformed host cells, transgenic plants and plant parts, and antibody compositions.

REFERENCES:
patent: 6211437 (2001-04-01), Briggs et al.
patent: 6310273 (2001-10-01), Gilchrist et al.
patent: 2003/0008785 (2003-01-01), Reed
patent: WO 00/09664 (2000-02-01), None
patent: WO 00/26391 (2000-05-01), None
patent: WO 01/59108 (2001-08-01), None
patent: WO 01/66696 (2001-09-01), None
patent: WO 02/22822 (2002-03-01), None
Broun et al. Catalytic plasticity of fatty acid modification enzymes underlying chemical diversity of plant lipids. Science. 1998 N 13;282(5392):1315-7.
Holinger et al. Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activatio of caspases. J Biol Chem. May 7, 1999;274(19):13298-304.
Kawai et al. Evolutionally conserved plant homologue of the Bax inhibitor-1 (Bl-1) gene capable of supressing Bax-induced ce death in yeast(1). FEBS Lett. Dec. 31, 1999;464(3):143-7.
Kawai et al., Oryza sativa Bl-1 mRNA for Bax inhibitor-1, complete cds. GenBank Accession No. AB025926, Mar. 4, 2000.
Mittler R. et al. Inhibition of Programmed Cell Death in Tobacco Plants during a Pathogen-Induced Hypersensitive Response at Low Oxygen Pressure. Plant Cell. Nov. 1996;8(11):1991-20.
Segal et al. Zinc fingers and a green thumb: manipulating gene expression in plants. Curr Opin Plant Biol. Apr. 2003;6(2):163-8. Review.
Cotter et al., “Cell death (apoptosis) in cell culture systems”, (1995)TIBTECH13:150-155.
Kawai-Yamada et al., “Mammalian Bax-induced plant cell death can be down-regulated by overexpression ofArabidopsis Bax Inhibitor-1(AtBI-1)”, (2001)Plant Biology98(21):12295-12300.
Mitsuhara et al., “Animal cell-death suppressors BcI-xLand Ced-9 inhibit cell death in tobacco plants”, (1999)Current Biology9(14):775-778.
Oltvai et al., “BcI-2 Heterodimerizes In Vivo with a Conserved Homolog, Bax, That Accelerates Programmed Cell Death”, (1993)Cell74:609-619.
Pennell et al., “Programmed Cell Death in Plants” (1997) PlantCell9:1157-1168.
Sanchez et al., “AtBI-1, a plant homologue of Bax Inhibitor-1, suppresses Bax-induced cell death in yeast and is rapidly upregulated during wounding and pathogen challenge”,Plant Journal21(4):393-399.
Wei et al., “Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondiral Dysfunction and Death”, (2001)Science292:727-730.
GAP Nucleotide Comparisons of the Seven Maize Bax Inhibitor Genes to Each other using Nucleotide Coding Regions; 26 pages.
BLAST results ofZea maysBax Inhibitor (Zm-BI) genes with public sequence databases (NR, NT, public EST, and GeneSeq); 31 pages.
GAP DNA Sequence Alignment Analysis; 9 pages.
GAP DNA Sequence Alignment Analysis; 11 pages.
GAP DNA Sequence Alignment Analysis; 47 pages.
Kawai et al., Evolutionally conserved plant homologue of the Bax Inhibitor-1 (Bl-1) gene capable of supressing Bax-induced cell death in yeast, FEBS Letters 464 (1999) 143-147.
Database Gen Bank Accession No. BG321220, Singh et al., Expressed Sequence Tags from Cold-Stressed maize Seedlings, Gene Sequence (Feb. 27, 2001).
Database GenBank Accession No. AB025926, Kawat et al., Evolutionally conserved plant homologue of the BAX inhibitor-1 (BI-1) gene capable of suppressing Bax-induced cell death in yeast, Gene Sequence (Mar. 4, 2000).

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