Anti-anxiety and anti-parkinsonian 1-aminoalkyl-2-endo-chloro-7,

Details Anti-anxiety and anti-parkinsonian 1-aminoalkyl-2-endo-chloro-7, Anti-anxiety and anti-parkinsonian 1-aminoalkyl-2-endo-chloro-7,

1976-10-08

1978-10-03

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

260239A, 260239B, 26029356, 2603265C, 2603268, 260563P, 424244, 424274, 424325, A61K 31445, C07D21114

Patent

active

041184998

ABSTRACT:
1-Aminoethyl, 1-aminopropyl and 1-aminobutyl derivatives of 7,7-dimethylnorbornane are described. The amino groups are optionally substituted, for example by alkyl groups, or may be saturated heterocyclic amino groups. The alkylene group at the 1-position can also be substituted, and the 2-position can be substituted by chlorine. The compounds have CNS activity.

REFERENCES:
patent: 2843587 (1958-07-01), De Benneville
patent: 3483254 (1969-12-01), Shen et al.
Index Chemicus, vol. 34, 118103 (1969). [Minardi, G. et al., Annali di Chimica, vol. 59 (#4), 335-349 (1969). ]
Migrdichian, V., Organic Synthesis, Reinhold Publishing Corp., NY, 1957, vol. I, p. 496 and vol. II., pp. 1427-1428.
Theilheimer, W., Synthetic Methods of Organic Chemistry, Interscience, NY, 1959, vol. 13, p. 66.
Fieser, L. F. and Fieser, M., Advanced Organic Chemistry, Reinhold Publishing Corp., NY, 1961, p. 495.
Smith, P. A. S., Chemistry of Open-Chain Organic Nitrogen Compounds, vol. I, W. A. Benjamin, NY, 1965, p. 25.
House, H. O., Modern Synthetic Reactions, 2nd Edition, W. A. Benjamin, Menlo Park, Cal., 1972, pp. 18 and 72.
Chemical Abstracts, 82:16403m (1975) [German Offen. 2,410,492, May, p., 9/26/74].

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