Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-11-21
2006-11-21
Stockton, Laura L. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S314700
Reexamination Certificate
active
07138421
ABSTRACT:
This invention relates to anti-androgenic N-[ω-[3-[4-cyano-3-(trifluoromethyl)-phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]alkyl]-substituted pyrrolidines of general formula I,with a strongly pronounced antiproliferative profile of action; process for the production of the compounds of general formula I, pharmaceutical preparations and the use for the production of pharmaceutical agents.
REFERENCES:
patent: 5411981 (1995-05-01), Gaillard-Kelly et al.
patent: WO 97/00071 (1997-01-01), None
patent: WO 00/37430 (2000-06-01), None
Golub et al., Science, vol. 286, Oct. 15, 1999, pp. 531-537.
International Search Report dated Dec. 8, 2004 issued in PCT/EP2004/004225.
M. E. Van Dort, et al., American Chemical Society, (2000), pp. 3344-3347.
Cleve Arwed
Hoffmann Jens
Parczyk Karsten
Reichel Andreas
Schulze Volker
Millen White Zelano & Branigan P.C.
Schring Aktiengesellschaft
Stockton Laura L.
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