Anti-androgenic amides

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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260465D, A61K 31275, C07C12178

Patent

active

042397766

ABSTRACT:
The disclosure relates to novel 3,4-disubstituted-branched-chain-acylanilides, processes for their manufacture and pharmaceutical compositions containing them. The compounds possess anti-androgenic activity. Representative of the compounds disclosed is 3,4-dicyanoisobutyranilide.

REFERENCES:
patent: 3794683 (1974-02-01), Gassner et al.
patent: 3875229 (1975-04-01), Gold
patent: 3995060 (1976-11-01), Neri et al.
Grivsky et al., Ind. Chim. Belg., vol. 39, pp. 490-500, (1974).

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