Anti-.alpha.V-integrin monoclonal antibody

Details Anti-.alpha.V-integrin monoclonal antibody Anti-.alpha.V-integrin monoclonal antibody

1995-12-19

1999-11-16

Chan, Christina Y.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

4241301, 4241331, 4241381, 4241411, 4241521, 4241721, 435 7021, 435330, 435326, 435332, 435346, 435452, 5303871, 5303873, 5303877, 5303882, 53038822, 5303888, 536 2353, A61K 39395, C07K 1628, C12N 1513, C12N 512

Patent

active

059852780

ABSTRACT:
The invention relates to a novel monoclonal antibody, a hybridoma cell line producing said antibody, DNA sequences coding for said antibody, and amino acid sequences. The monoclonal antibody, a preferred embodiment of which is named 17E6, has the following properties:

REFERENCES:
Osband et. al Immunol. Today 11:193-195 (1990).
Dermer Biotechnology 12:320 (1994).
Dillman J Clin. Oncol. 12:1497-1515 (1994).
Lehmann et al., Cancer Research 54:2102-2107 (1994).
Cheresh et al., J. Biol. Chem. 262:17703-17711 (1987).
Mitjans et al., J. Cell Sci. 108:2825-2838 (1995).
Marshall et al., J. Cell Sci. 108:1227-1238 (1995).

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