Anti-allergic esters, acetal ethers, thioethers and nitrogen sub

Details Anti-allergic esters, acetal ethers, thioethers and nitrogen sub Anti-allergic esters, acetal ethers, thioethers and nitrogen sub

1988-07-22

1990-02-20

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142345, 514242, 514249, 514253, 514312, 514254, 544127, 544182, 544238, 544322, 544328, 544331, 544350, 544405, 546122, 546155, A61K 31435, C07D 4704

Patent

active

049026933

ABSTRACT:
Esters, acetal ethers, thioethers and nitrogen substituted derivatives of certain bicyclic compounds are disclosed which are useful as anti-allergic, anti-inflammatory and/or cytoprotective agents and in treatment of hyperproliferative skin disease. Pharmaceutical compositions and methods of treatment employing such compounds are also disclosed.

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Merchant et al., "Synthesis of Some Derivatives of 4-Hydroxyl-1-Phenyl-2H(1)Quinodone", Current Science, vol. 49, No. 1, pp. 20-21, Jan. 5, 1980.
Wittman et al., "Syntheses of Heterocycles, CCV111[1]. The Chemistry of Visional Triketones, XI[2]. Ringcontractions of Quinolinetriones", Z. Naturforsch, 33b, pp. 1540-1546 (1978).
Suzuki et al., "A Synthesis of 3-Amino-4-Hydroxyquinolin-2(1H)-One Derivatives via Oxazolo[4,5-c]quinolin-4(5H)-ones", Chem. Pharm. Bull., 25(10), pp. 2602-2607 (1977).

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