Anti-allergic compositions and their use

Details Anti-allergic compositions and their use Anti-allergic compositions and their use

1984-04-26

1986-09-02

Rosen, Sam

Drug, bio-affecting and body treating compositions

Lymphokine

424 91, A61K 39385, A61K 3936

Patent

active

046095470

ABSTRACT:
Pharmaceutical compositions are described for anti-allergy therapy comprising an allergen or allergen extract, polysarcosine having an average molecular weight in the range of 2,000 to 12,000 and a chemical linking group connecting a reactive site on the polysarcosine to an amino group on the allergen or allergen extract, the reactive site on the polysarcosine being a H(CH.sub.3)N--, the allergen extract being an extract from an allergen selected from pollens, weeds, house dust mites and venoms, and the chemical linking group having the formula --CO--B--CO where B is a hydrocarbon chain of 1-4 carbon atoms. The disclosure also describes the analogous conjugates.

REFERENCES:
patent: 3619371 (1971-11-01), Crook et al.
patent: 4152411 (1979-05-01), Schall

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