Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-08-15
2006-08-15
Tsang, Cecilia J. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S290000
Reexamination Certificate
active
07091224
ABSTRACT:
The invention relates to anthranilic acid amide derivatives of formula (I), wherein R1represents H or lower alkyl, R2represents H or lower alkyl, R3represents perfluoro lower alkyl, and X is O or S, or an N-oxide or a tautomer thereof, to salts of such anthranilic acid amides, their N-oxides and their tautomers; processes for the preparation thereof, the application thereof for the treatment of the human or animal body, the use thereof—alone or in combination with one or more other pharmaceutically active compounds—for the treatment especially of a neoplastic disease, such as a tumor disease, of retinopathy or age—related macular degeneration; a method for the treatment of such a disease in animals, especially in humans, and the use of such a compound—alone or in combination with one or more other pharmaceutically active compounds—for the manufacture of a pharmaceutical preparation for the treatment of a neoplastic disease, of retinopathy or age-related macular degeneration.
REFERENCES:
patent: 00 27820 (2000-05-01), None
patent: 0027820 (2000-05-01), None
Breier et. al., “The role of vascular endothelial growth factor in blood vessel formation”, Trends in Cell Biology (vol. 6), Dec. 1996.
Hcaplus 132:347491.
Bold Guido
Furet Pascal
Manley Paul W
McNally Lydia T.
Novartis AG
Robinson Binta
Tsang Cecilia J.
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