Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-01-25
2009-12-01
Duffy, Patricia A. (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S295000
Reexamination Certificate
active
07625903
ABSTRACT:
The present invention relates to a compound represented by the following formula:or a pharmaceutically acceptable salt thereof;where R1, R2, R3, R4, r and s are as previously defined. Compounds of the present invention are useful in the treatment of diseases associated with Aurora kinase activity such as cancer.
REFERENCES:
patent: 2006/0009453 (2006-01-01), Geuns-Meyer et al.
patent: 1184376 (2005-02-01), None
patent: 1598343 (2005-11-01), None
patent: WO0164656 (2001-09-01), None
patent: WO03037877 (2003-05-01), None
patent: WO03078404 (2003-09-01), None
patent: WO2004074244 (2004-09-01), None
patent: WO2004080980 (2004-09-01), None
patent: WO2005016894 (2005-02-01), None
patent: WO2005026130 (2005-03-01), None
patent: WO2005026158 (2005-03-01), None
patent: WO2006021454 (2006-03-01), None
patent: WO2007089768 (2007-08-01), None
patent: WO2008073687 (2008-06-01), None
Goldman et al [Editors] “Chapter 198: Principles of Cancer Therapy.” Cecil's Textbook of Medicine (Twenty-First Edition, vol. 1). W.B. Saunders Company, 2000. pp. 1060-1074.
Cancer, Merck Manual Home Edition, pp. 1-2, Retrieved on Mar. 11, 2009.
Cheethem, et al, “Crystal Structure of Aurora-2, an Oncogenic serine/Threonine Kinase.”Journal of Biological Chemistry., Nov. 8, 2002: 277:42419-42422: pp. 44420-44421, Fig 1 and 2.
Bryan Deborah L.
Johnson Neil W.
Duffy Patricia A.
Lemanowicz John
Pagonakis Anna
SmithKline Beecham Corporation
Willis Reid S.
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